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"Margaret of Austria " (details from "Portrait of Margaret of Austria, Queen of Spain (1584-1611) Spouse of Philip or Felipe IV ") (see related A | B), 1609 Bartolome Gonzalez y Serrano (1564-1627) El Prado Museum , Madrid, Spain

Note the prominent jaw (mandible), the "Cupid bow" of the upper lip mucosa  and the related deep philtrum above it. For other features and comment see another version of her portrait. These "traits" or "sings" are "signals" of an autosomal dominant "phenotype" or physical signs inherited by nearly one half of the legitimate and "bastards" or "natural" collateral children engendered by affected members Habsburg or Hapsburg dynastic families. 

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