Durer dissected cadavers and produced a book of anatomical human perspectives for artists.
Clinicians may note bilateral "crumpled" ears and alopecia. The dramatic degree of megalocephaly or macrocrania argues against to possibility of syndromes such as Cerebral Gigantism, Neurofibromatosis type 1, etc. - hydrocephaly appears to be a better diagnostic choice. Also note the "squint" or the divergent strabismus of the left eye - in that era, tuberculosis was common - one pediatric manifestation was tuberculous meningitis - perhaps illustrated here by Durer. ( W. Wertelecki, M.D.)