ARTHROGRYPOSIS - EDWARD SYNDROME - TRISOMY 18?
"Arthrogryposis" (see related A), 1841 Adolph Wilhelm Otto (1786-1845)
This historic image (1841) illustrates several points. Presented as an illustration of AMC or arthrogryposis multiplex congenita, in fact, it shows other signs suggesting a diagnosis that at the time was unknown. Therefore, it demonstrates the sensitivity of the artists to note significant signs without realizing that they were signals that could be interpreted more than a century later. Clearly, the artist had "open eyes". The question is how many clinicians have open eyes. Increasingly, clinicians are blinded by what they know in the sense that what they do not know, they do not see. For clinical comments sustaining the arguments above, please view the companion posting.