PERSISTENT ALCOHOL CONSUMPTION RESULTS IN DEPENDENCY (ALCOHOLISM)
"Malle Babbe" (see details A | B) (see related A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R), 1633 Frans Hals (known as Frans Hals the Elder) (c.1582-1666) Gemaldegalerie, Berlin, Germany
Symbolic owl implying that alcoholism is antithetical to wisdom. Alcohol damages the brain before birth because it is a teratogen and postnatally by killing neurons, particularly cerebral ones.
(This is the core image of a gallery concerning alcohol - note links to related images).